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Updated: Aug 17, 2026

Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
Published on: May 21, 2013
[Tissue engineering of cartilagenous tissue. Vital cryopreservation]
E Viviente Rodríguez1, H Sudhoff, A Capitán
1Servicio de ORL, Hospital General Universitario, Murcia.
Abstract:
The characteristics of in vitro synthesized cartilage tissue using tissue engineering techniques before and after cryopreservation are described. We determined cell survival, growth of extracellular matrix (collagen and proteoglycan) using a computer analysis system, and characterized the cell phenotype with a monoclonal antibody specific for collagen type II. Chondrocytes maintained a differentiated phenotype with collagen and proteoglycan synthesis before and after cryopreservation.

