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Acinetobacter sepsis in newborns

A Mishra1, S Mishra, G Jaganath

  • 1Department of Pediatrics, Tata Main Hospital, Jamshedpur.

Indian Pediatrics
|August 26, 1998
PubMed
Summary
This summary is machine-generated.

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Acinetobacter sepsis, a serious neonatal infection, can affect full-term infants and presents similarly to other Gram-negative septicemias. Ciprofloxacin shows promise for treating resistant cases, though mortality remains a concern.

Area of Science:

  • Neonatal Medicine
  • Infectious Diseases
  • Bacteriology

Background:

  • Acinetobacter species are increasingly recognized as significant nosocomial pathogens.
  • Neonatal sepsis poses a substantial threat to infant survival and long-term health.

Purpose of the Study:

  • To elucidate the clinical and epidemiological characteristics of Acinetobacter sepsis in neonates.
  • To identify risk factors, clinical presentations, complications, and treatment outcomes.

Main Methods:

  • Retrospective study design.
  • Analysis of case records from 79 neonates with blood culture-confirmed Acinetobacter infection.
  • Data collected on clinical and epidemiological factors.

Main Results:

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  • Acinetobacter septicemia incidence was 11.1/1000 live births.
  • Cases peaked between May and September, affecting both term and preterm infants.
  • Common symptoms included respiratory distress and feeding refusal; complications included meningitis and necrotizing enterocolitis.

Conclusions:

  • Nosocomial Acinetobacter sepsis can impact term infants and mimics other Gram-negative septicemias.
  • Life-threatening complications are possible, highlighting the need for effective treatment.
  • Ciprofloxacin demonstrated high sensitivity and potential utility in resistant infections.