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Infertility in women: an update
1College of Pharmacy, Medical University of South Carolina, Charleston 29425, USA. carsonds@smtpgw2.musc.edu
Journal of the American Pharmaceutical Association (Washington, D.C. : 1996)
|August 26, 1998
Summary
Pharmacologic therapy for female infertility focuses on hormonal and cellular interactions. This review covers key medications used to treat anovulation and related endocrine disorders.
Area of Science:
- Reproductive Endocrinology
- Pharmacology
Background:
- Female infertility involves complex hormonal and cellular interactions.
- Identifying the precise cause of infertility is often challenging.
Purpose of the Study:
- To review current pharmacologic therapies for female infertility disorders.
- To provide an overview of medications used to address common causes of infertility.
Main Methods:
- Review of current clinical literature on infertility pharmacotherapy.
- Synthesis of information on commonly prescribed medications.
Main Results:
- Pharmacotherapy targets anovulation, secondary ovarian failure, hypothalamic-pituitary dysfunction, and hyperprolactinemia.
- Key medications reviewed include clomiphene, human chorionic gonadotropin, menotropins (human menopausal gonadotropin, urofollitropin), gonadotropin-releasing hormone, and dopamine agonists.
- Current infertility treatment is described as more art than science due to diagnostic complexities.
Conclusions:
- Pharmacists can play a supportive role by providing information and monitoring patients.
- Pharmacists can assist with practical instructions and identifying psychologic stress in families undergoing infertility treatment.