[Symptomatic coronary disease associated with mitral insufficiency: surgical strategy]

In recent years coronary artery bypass grafting (CABG) has been extended to include patients with very low left ventricular ejection fractions (LVEF), also frequently with co-existing mild to moderate mitral valve regurgitation (MR). The question is, should MR be corrected simultaneously with a myocardial revascularization or not? Between January 1990 and December 1996, 82 patients with preoperative LVEF < or = 0.25 and echocardiographic evidence of co-existing MR without chordal or papillary muscle rupture (Grade I-28%, II-35%, III-32% and IV-5%) underwent primary CABG. None of them underwent simultaneous mitral valve surgery. The mean preoperative LVEF was 0.17 +/- 0.04 (0.10-0.25), mean PAP 43.8 +/- 15.9 mmHg. An average of 4.4 +/- 1.5 grafts/ patient were placed. The overall mortality was 3.7% (3/82). Transient postoperative low cardiac output syndrome occurred in 24 patients (29%). Thirty-two patients (39%) had no postoperative complications at all. Seventy-nine hospital survivors were followed up over a period of 18 months (6-48 months) on average. There was one death (8 months post-operatively) and 2 graft occlusions, not requiring redo surgery. At the end of follow up echocardiography showed that 45 patients had no MR at all and 28 patients had MR-Grade I, a total of 73 patients (94%). Five patients had Grade II-III MR, none of them requiring mitral valve surgery. All patients improved their NYHA functional class, from 3.5 +/- 0.7 to 1.8 +/- 0.5 and the LVEF from 0.17 +/- 0.04 to 0.46 +/- 0.08, p < 0.001. Moderate to severe co-existing MR (Grade II-IV) seems to normalize after the myocardial revascularization and should therefore not be surgically corrected at the primary operation, if there are no echocardiographic evidence of chordal or papillary muscle rupture. Peroperative control echocardiography is recommended.