[Responses and physiological modifications of intestinal sucrase in rats fed diets containing various carbohydrates]

Weaning rats were submitted during 3 months to complet and balanced diets where only glucidic constituent varied. They were sacrified when fed or after 16 h fasting. 1. The value of intestinal sucrose K(M) is higher in rats fed on glucose dietary than in rats fed on sucrose, fructose or glucose + fructose dietary. These modifications are independant of the states of digestion. 2. The V(MAX) is diversely influenced by the states of digestion: hydric diet increases the V(MAX) in animals fed on sucrose diet when intestinal repletion has the same effect in animals receiving glucose diet. Fructose diet decreases it irreversibility in both cases. 3. Growth of animals is sagging respectively in order from sucrose and glucose diets to glucose + fructose and fructose diets, then weight of organes is unaffected. It was noted that perirenal and epididymal fats are more abundant in rats nourished with glucose diet than with fructose diet. 4. The glucoregulation is correctly effectued in either starved or fed animals and shows an available adaptation of organism in energetic utilisation of various studied sugars. Plasmatic, hepatis and intestinal free fatty acids levels are constant and equal in all series of expements in spite of important variations of reverse fat.