Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Radioiodine secretion in tears

S M Bakheet1, M M Hammami, A Hemidan

  • 1Department of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
|August 26, 1998
PubMed
Summary

Radioiodine is secreted in tears, confirmed by measuring radioactivity in tear samples from a patient treated with thyroxine. This finding suggests potential risks to the lacrimal gland from radioiodine treatments.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

X-linked adrenoleukodystrophy. The Saudi experience.

Neurosciences (Riyadh, Saudi Arabia)·2013
Same author

Documentation of ethical conduct of human subject research published in Saudi medical journals.

Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit·2012
Same author

Medical chaperoning at a tertiary care hospital in Saudi Arabia: survey of physicians.

Journal of medical ethics·2009
Same author

X-linked adrenoleukodystrophy. The Saudi experience.

Saudi medical journal·2001
Same author

Radioiodine uptake in the head and neck.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·2001
Same author

F-18 FDG positron emission tomography in primary breast non-Hodgkin's lymphoma.

Clinical nuclear medicine·2001

Area of Science:

  • Nuclear Medicine
  • Ophthalmology
  • Endocrinology

Background:

  • Radioiodine secretion into tears has been suggested by scintigraphic data.
  • This study quantifies radioiodine levels in tears from a patient undergoing thyroxine therapy post-thyroid ablation.

Observation:

  • Tear samples were collected over 24 hours after oral administration of iodine-123 (123I).
  • Radioactivity was measured in tear samples using a well counter, with corrections for decay and counting efficiency.

Findings:

  • Radioiodine was detected in tears from 15 minutes up to 24 hours post-ingestion, peaking around 60 minutes.
  • An estimated 56 kBq of radioactivity was secreted in tears within the first 4 hours, representing approximately 0.01% of the administered dose.

Related Experiment Videos

Implications:

  • Ingested radioiodine is appreciably secreted into tears.
  • Further research is needed to assess potential lacrimal gland damage from high-dose radioactive iodine (131I) treatments.