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Related Experiment Videos

Degenerative changes in the human cricoarytenoid joint

F P Paulsen1, B N Tillmann

  • 1Department of Anatomy, Christian-Albrechts-University of Kiel, Germany. fpaulsen@anat.uni-kiel.de

Archives of Otolaryngology--Head & Neck Surgery
|August 26, 1998
PubMed
Summary

Degenerative changes in the cricoarytenoid joint, affecting vocal ligament closure, are common in individuals over 40. These alterations contribute to age-related voice changes and reduced vocal quality.

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Area of Science:

  • Gerontology
  • Otolaryngology
  • Anatomy

Background:

  • Voice changes are a natural part of aging.
  • Alterations in the cricoarytenoid joint are a suspected cause of age-related voice changes.
  • The role of the cricoarytenoid joint in vocal aging is debated.

Purpose of the Study:

  • To investigate degenerative changes in the cricoarytenoid joint.
  • To correlate these changes with age and vocal function.

Main Methods:

  • Histological, immunohistochemical, and scanning electron microscopy were used.
  • Analyzed 42 cricoarytenoid joints from 21 body donors (ages 42-98).

Main Results:

  • Distinct joint surface alterations were observed in individuals over 40.

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  • Fibrillation of articular cartilage and chondrocyte clustering were noted.
  • Positive collagen type III and I reactions in superficial cartilage.

    • Conclusions:

    • Chondrocyte proliferation, altered collagen synthesis, and surface fibrillation indicate joint degeneration.
    • These changes may impair arytenoid cartilage movement and vocal ligament closure.
    • Structural changes can lead to reduced vocal quality and intensity due to air leakage.