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Early rheumatoid disease. I. Onset

A Fleming, J M Crown, M Corbett

    Annals of the Rheumatic Diseases
    |August 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Early rheumatoid disease onset in patients shows a near equal sex incidence. Insidious, symmetrical upper limb involvement is common, with older patients experiencing worse outcomes.

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    Area of Science:

    • Rheumatology
    • Clinical Medicine
    • Epidemiology

    Background:

    • Rheumatoid disease (RD) is a chronic inflammatory condition.
    • Understanding early disease features and prognosis is crucial for patient management.

    Purpose of the Study:

    • To describe the initial clinical features of rheumatoid disease.
    • To evaluate prognostic factors influencing long-term outcomes in RD patients.

    Main Methods:

    • Prospective follow-up of 102 patients diagnosed with rheumatoid disease within their first year.
    • Assessment of disease characteristics at onset and patient outcomes after a mean of 4.5 years.

    Main Results:

    • The male:female ratio at onset was approximately 3:4, indicating near-equal sex incidence.

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  • Disease onset occurred more frequently in colder months, often insidious, symmetrical, and affecting upper limbs.
  • Older age at onset correlated with poorer outcomes.
  • Insidious onset and early symmetrical involvement trended towards a worse prognosis.

    • Conclusions:

    • Early rheumatoid disease presentation is characterized by specific demographic and clinical features.
    • Age and initial disease progression patterns are important indicators for rheumatoid disease prognosis.