Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Enterococci and vancomycin resistance

G L French1

  • 1Department of Microbiology, United Medical School, Guy's Hospital, London, United Kingdom.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|August 26, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Point-of-care universal screening for meticillin-resistant Staphylococcus aureus: a cluster-randomized cross-over trial.

The Journal of hospital infection·2016
Same author

Implications of targeted versus universal admission screening for meticillin-resistant Staphylococcus aureus carriage in a London hospital.

The Journal of hospital infection·2014
Same author

A request for an alliance in the battle for clean and safe hospital surfaces.

The Journal of hospital infection·2013
Same author

Low prevalence of meticillin-resistant Staphylococcus aureus carriage at hospital admission: implications for risk-factor-based vs universal screening.

The Journal of hospital infection·2013
Same author

The role of 'no-touch' automated room disinfection systems in infection prevention and control.

The Journal of hospital infection·2012
Same author

Impact of the suspending medium on susceptibility of meticillin-resistant Staphylococcus aureus to hydrogen peroxide vapour decontamination.

The Journal of hospital infection·2012
Same journal

Anticalcitonin: Limited utility of a context-dependent biomarker demonstrated in another real-world data set.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Procalcitonin Testing in Community-Acquired Pneumonia.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Wanted: A Relevant Correlate of Protection for Dengue Vaccines.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Safety and Immunogenicity of the Live-Attenuated Quadrivalent Dengue Vaccine V181 Compared With Butantan-DV Among Healthy Adults in Brazil: A Randomized, Double-Blind, Phase 2 Trial.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Low Post-Treatment Recurrence After a Shortened All-oral Regimen for Pulmonary Rifampicin- or Multidrug-Resistant Tuberculosis in Individuals without Prior Second-Line Drug Exposure in Kazakhstan.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same journal

Sepsis Diagnostic Excellence and its Association with Mortality in Adults with Potential Infection.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
See all related articles

The rise of antibiotic-resistant bacteria is concerning, especially glycopeptide-resistant enterococci. These resistant strains may spread to other dangerous bacteria, posing a significant public health threat.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Antimicrobial Resistance

Background:

  • Increasing incidence of infections caused by multiply antibiotic-resistant gram-positive bacteria.
  • Limited treatment options, with glycopeptides (vancomycin, teicoplanin) as a last resort.
  • Emergence of transferable high-level glycopeptide resistance in enterococci is a significant concern.

Purpose of the Study:

  • To highlight the growing threat of glycopeptide-resistant enterococci (GRE).
  • To discuss the potential for GRE to spread resistance to other pathogens.
  • To identify factors contributing to the emergence and spread of GRE.

Main Methods:

  • Literature review and synthesis of current research on antibiotic resistance.
  • Analysis of the epidemiology and transmission dynamics of enterococci.

Related Experiment Videos

  • In vitro experimental data on resistance transfer.

    • Main Results:

    • Enterococci readily colonize the bowel and spread rapidly in hospitals.
    • Transferable high-level glycopeptide resistance has been observed in enterococci.
    • Experimental in vitro transfer of resistance to Staphylococcus aureus has been achieved.
    • Antibiotic use (aminoglycosides, cephalosporins, quinolones, glycopeptides) and avoparcin in animal feed promote GRE.

    Conclusions:

    • Enterococci are a potential vehicle for disseminating glycopeptide resistance to other gram-positive bacteria.
    • Continued emergence of GRE poses a serious threat to public health.
    • Stewardship of antibiotic use and monitoring of resistance are critical.