Use of homology modeling to predict residues involved in ligand recognition

A functioning chimera of the cyclic nucleotide-binding domain from the bovine retinal rod ion channel and the DNA-binding domain from catabolite gene-activating protein.

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Role for ATM in DNA damage-induced phosphorylation of BRCA1.

Cancer research·2000

Mutating three residues in the bovine rod cyclic nucleotide-activated channel can switch a nucleotide from inactive to active.

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Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity.

The Journal of biological chemistry·2000

Conformational studies of Actinobacillus actinomycetemcomitans leukotoxin: partial denaturation enhances toxicity.

Biochimica et biophysica acta·2000

The effects of ibogaine on dopamine and serotonin transport in rat brain synaptosomes.

Brain research bulletin·1999

Comparative methods for recombinant production and characterization of 1-deoxy-D-xylulose-5-phosphate synthase from bacterial and apicomplexan sources.

Methods in enzymology·2026

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Methods in enzymology·2026

Thiamine pyrophosphate-dependent enzymes in Toxoplasma gondii and functional significance of an apicoplast-localized pyruvate dehydrogenase.

Methods in enzymology·2026

Biochemical and cryo-EM studies of the pyruvate dehydrogenase complex from native cell extracts.

Methods in enzymology·2026

Synthesis of phosphonate and phosphinate analogs of 2-oxo acids for site-specific inhibition of thiamine-diphosphate-dependent dehydrogenases of 2-oxo acids in vivo.

Methods in enzymology·2026

Use of dihydroxyacetone synthase for the assimilation of methanol in E. coli.

Methods in enzymology·2026

Proteome-guided drug discovery maps and mitigates therapeutic degrader toxicity.

Nature chemical biology·2026

Inhibition of vasculogenic mimicry by 22-benzyloxydaphlongaminone via glycolysis suppression.

The Journal of antibiotics·2026

Integrating Fragment Screening and Covalent Chemistry to Drug DNA-Binding Proteins: RAD52 as a Case Study.

Journal of the American Chemical Society·2026

Outdoor attractive targeted sugar bait Phase III trials for malaria control in Kenya, Mali, and Zambia: An individual participant data meta-analysis.

PLOS global public health·2026

Integrating in vitro and in silico correlation of thiazole-based carboxamide derivatives as promising SARS-CoV-2 papain-like protease inhibitors: a versatile approach for COVID-19 therapy.

Zeitschrift fur Naturforschung. C, Journal of biosciences·2026

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Bioinformatics (Oxford, England)·2026

Related Experiment Videos

Use of homology modeling to predict residues involved in ligand recognition

Related Concept Videos

A functioning chimera of the cyclic nucleotide-binding domain from the bovine retinal rod ion channel and the DNA-binding domain from catabolite gene-activating protein.

Role for ATM in DNA damage-induced phosphorylation of BRCA1.

Mutating three residues in the bovine rod cyclic nucleotide-activated channel can switch a nucleotide from inactive to active.

Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity.

Conformational studies of Actinobacillus actinomycetemcomitans leukotoxin: partial denaturation enhances toxicity.

The effects of ibogaine on dopamine and serotonin transport in rat brain synaptosomes.

Comparative methods for recombinant production and characterization of 1-deoxy-D-xylulose-5-phosphate synthase from bacterial and apicomplexan sources.

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Thiamine pyrophosphate-dependent enzymes in Toxoplasma gondii and functional significance of an apicoplast-localized pyruvate dehydrogenase.

Biochemical and cryo-EM studies of the pyruvate dehydrogenase complex from native cell extracts.

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Use of homology modeling to predict residues involved in ligand recognition

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