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Related Experiment Videos

Screening test for decompression sickness

G B Hart

    Aviation, Space, and Environmental Medicine
    |September 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Fibrin-fibrinogen degradation products (FDP) tests may help screen patients with diving-related illnesses. Positive FDP tests correlate with serious neurologic symptoms in decompression sickness, potentially guiding hyperbaric oxygen therapy.

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    Area of Science:

    • Diving Medicine
    • Hematology
    • Hyperbaric Medicine

    Background:

    • Diving activities can lead to various health issues, including decompression sickness.
    • Disseminated intravascular coagulation (DIC) is a potential complication in severe cases.
    • Fibrin-fibrinogen degradation products (FDP) are markers associated with coagulation disorders.

    Purpose of the Study:

    • To evaluate the utility of FDP tests in patients with diving-related illnesses.
    • To determine if FDP levels correlate with the severity of decompression sickness and neurologic involvement.
    • To assess the FDP test as a potential screening tool for guiding hyperbaric oxygen therapy (OHP).

    Main Methods:

    • Fibrin-fibrinogen degradation products (FDP) tests were conducted on 18 patients with a history of diving-related illness.

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  • FDP testing was performed prior to initiating hyperbaric oxygen therapy (OHP).
  • Patient outcomes and FDP test results were correlated with clinical presentation and treatment response.

    • Main Results:

    • Eight patients with serious neurologic signs had positive FDP tests and required repetitive OHP.
    • Six patients with negative FDP tests presented with local musculoskeletal complaints and improved after one OHP session.
    • Three patients with unrelated diseases had normal FDP levels. One patient with paraplegia from prior treatment had a positive FDP test.

    Conclusions:

    • Positive FDP tests in diving-related illness may indicate disseminated intravascular coagulation (DIC).
    • The FDP test shows promise as a screening tool to help delineate appropriate therapy for decompression sickness.
    • FDP testing could aid in stratifying patients and guiding the intensity of hyperbaric oxygen treatment.