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Ultrasmall immunogold particles: important probes for immunocytochemistry
J M Robinson1, T Takizawa, D D Vandré
1Department of Cell Biology, Neurobiology, and Anatomy, Ohio State University, Columbus 43210, USA.
Microscopy Research and Technique
|August 26, 1998
Abstract:
In this article, we review the immunocytochemical literature with respect to a comparison between conventional colloidal gold and ultrasmall gold particles as immunoprobes. We discuss the relative advantages and disadvantages of each of these types of particles for immunocytochemical applications. We present results from our own laboratories, in which we compared these immunoprobes in selected experimental situations. In addition, we discuss our work on the use of a fluorescently labeled ultrasmall immunoprobe for correlative microscopy.