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Enteral yeast-selenium supplementation in preterm infants
1National Institute of Rheumatology and Physiotherapy, Budapest, Hungary.
Archives of Disease in Childhood. Fetal and Neonatal Edition
|August 26, 1998
Summary
Selenium-enriched yeast effectively boosted selenium levels in preterm infants in Hungary. This supplementation proved safe and beneficial for infants in low-selenium regions.
Area of Science:
- Nutritional Science
- Pediatric Medicine
- Biochemistry
Background:
- Low selenium levels pose risks to preterm infants.
- Hungary is identified as a low-selenium geographical area.
- Optimal selenium intake is crucial for infant development and health.
Purpose of the Study:
- To assess the bioavailability of selenium-enriched yeast.
- To evaluate selenium supplementation in preterm infants in a low-selenium region.
- To determine the safety and efficacy of selenium-enriched yeast.
Main Methods:
- A randomized study involving 36 preterm infants.
- Infants were divided into supplemented and non-supplemented groups.
- Supplemented infants received 5 micrograms of selenium via yeast daily.
Main Results:
- Serum selenium concentrations increased significantly in the supplemented group.
- Serum selenium levels decreased in the non-supplemented group over two weeks.
- No adverse effects or complications were reported with selenium supplementation.
Conclusions:
- Selenium-enriched yeast is a safe and effective method for short-term enteral selenium supplementation.
- This approach is suitable for preterm infants, particularly in selenium-deficient areas.
- The study supports the use of selenium-enriched yeast to improve selenium status in vulnerable infant populations.