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2-Pyrazolin-5-ones structurally related to certain analgesics and antipyretic drugs and their anti-inflammatory
1Department of Chemistry, Faculty of Science, Makerere University, Kampala, Uganda.
Abstract:
The anti-inflammatory activity of twenty six 2-pyraxolin-5-one derivatives (Ia-z) was studied using carrageenin induced paw edema in male albino rats. Compounds 1(1)-Ip exhibited moderate anti-inflammatory activity, while the rest were devoid of significant anti-inflammatory activity.