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[Tearing in a patient with glaucoma]

D P De Popa1, G Andreescu, C Albu

  • 1Clinica Oftalmologie-Spitalul Universitar Bucureşti.

Oftalmologia (Bucharest, Romania : 1990)
|August 26, 1998
PubMed
Summary

Glaucoma treatments like timolol and pilocarpine alter tear secretion and stability. Careful monitoring of glaucoma patients, especially older adults or those on specific medications, is crucial.

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Area of Science:

  • Ophthalmology
  • Pharmacology

Background:

  • Glaucoma treatment often involves topical medications that can affect ocular surface health.
  • Understanding the impact of these treatments on lacrimal secretion is vital for patient management.

Purpose of the Study:

  • To analyze changes in lacrimal secretion in glaucoma patients undergoing different topical treatments.
  • To correlate observed changes with specific drug classes and patient demographics.

Main Methods:

  • Schirmer's test was used to measure tear secretion.
  • Tear film break-up time (TBUT) was assessed to evaluate tear stability.
  • Observed effects of timolol and pilocarpine on lacrimal puncta and eyelid muscles were documented.

Main Results:

  • Timolol decreased lacrimal secretion (10-25%) and reduced tear film stability (lower TBUT).
  • Pilocarpine induced lacrimal puncta occlusion, increased tear secretion, and caused eyelid spasms.
  • Age and concurrent medication use (beta-blockers, neuroleptics) can exacerbate decreased lacrimal secretion.

Conclusions:

  • Topical glaucoma treatments significantly impact lacrimal function and tear film dynamics.
  • Regular monitoring is essential for glaucoma patients, particularly the elderly and those on medications affecting tear production.
  • These findings highlight the need for a comprehensive approach to managing glaucoma patients' ocular surface health.

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