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Update on plasminogen activator inhibitor-1

D Vaughan1

  • 1Cardiology Division, Vanderbilt University, Nashville, TN 37232, USA. doug.vaughan@mcmail.vanderbilt.edu

The Canadian Journal of Cardiology
|August 26, 1998
PubMed

Plasminogen activator inhibitor-1 (PAI-1) is produced by the endothelium and determines the rate and extent of fibrinolysis. Recent data on PAI-1 gene polymorphism and the potential role of glucose in regulating PAI-1 expression in vascular disease are reviewed.

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