Related Experiment Videos
A putative human papillomavirus type 57 new subtype isolated from plantar epidermoid cysts without intracytoplasmic
1Institute of Medical Science, St Marianna University School of Medicine, Miyamae, Kawasaki, Japan. hkita@med.kitasato-u.ac.jp
Abstract:
Human papillomavirus type 60 (HPV-60) is the only virus type that has been identified in epidermoid cysts. In this study, HPV-57 DNA was found in three out of 18 plantar epidermoid cysts with different histological features from HPV-60-associated cysts, using PCR and Southern hybridization. The HPV-57-associated cysts had features resembling an HPV-2-specific cytopathic effect. The sequences of two HPV-57 DNA clones isolated from two patients were identical, but differed at some positions from those of HPV-57a and HPV-57b. This putative new subtype was tentatively designated as HPV-57c, and may be associated with plantar epidermoid cysts showing histological features resembling the HPV-2 cytopathic effect.