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Updated: Aug 14, 2026

Mutagenesis and Functional Analysis of Ion Channels Heterologously Expressed in Mammalian Cells
15:28

Mutagenesis and Functional Analysis of Ion Channels Heterologously Expressed in Mammalian Cells

Published on: October 2, 2010

Characterization of three episodic ataxia mutations in the human Kv1.1 potassium channel

P Zerr1, J P Adelman, J Maylie

  • 1Vollum Institute, Oregon Health Sciences University, Portland 97201, USA.

FEBS Letters
|August 26, 1998
PubMed

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The Role of Ion Channels in Neuronal Computation

A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
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Voltage-gated ion channels are transmembrane proteins that open and close in response to changes in the membrane potential. They are present on the membranes of all electrically excitable cells such as neurons, heart, and muscle cells.
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