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Updated: Aug 11, 2026

The Spared Nerve Injury (SNI) Model of Induced Mechanical Allodynia in Mice
Published on: August 18, 2011
Results of suture of the sciatic nerve after missile injury
Objective:
To evaluate functional recovery after suture of the sciatic nerve after missile injury.
Methods:
We reviewed the outcome of 23 adults and four children who had the sciatic nerve sutured above the knee 3 to 14 weeks after missile injury and who were followed for 14 to 36 months.
Results:
In adults, useful motor recovery was significantly better after suture of tibial (83%) than peroneal (39%) nerves, after suture of nerves at the thigh (71%) than at the buttock (31%) level, and after end-to-end anastomosis (74%) than grafting (39%). Useful sensory function was recovered in 78% of tibial nerves. Fifty-seven percent of adults walked wearing special shoes or pads. Significantly better recovery occurred in children, who all walked with normal footwear.
Conclusion:
We advocate exploration of the sciatic nerve at any level within 3 months if no spontaneous recovery occurs after a missile injury. We do not advocate exploration of the sciatic nerve at the buttock level if only peroneal function is lost except in children.

