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Dynamic analysis of the three-phasic vascular response to histamine in coronary circulation
G L Rosić1, M Segal, I Andelković
1Institute of Physiology, Faculty of Medicine, University of Kragujevac, Yugoslavia.
Abstract:
In this work we tried to perform a dynamic analysis of coronary vascular response to histamine, using a simple mathematical analysis as a first step in the better understanding of complex histamine effects on coronary blood vessels of the isolated guinea pig heart. So, we defined more parameters, such as: I and delta I to quantify the intensity of coronary perfusion pressure (CPP) change, T and dt to quantify the time CPP change occurs and D to characterize the intensity and duration of CPP change, i.e. to quantify the dynamics of this change.
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