Changes in CNTF receptor alpha expression in rat skeletal muscle during the recovery period after hindlimb suspension

This study investigated whether modifications in the contractile function of rat muscle after 3 weeks of hindlimb suspension followed by different recovery periods were associated with changes in ciliary neurotrophic factor (CNTF) receptor alpha. CNTF receptor alpha was stronger in control extensor digitorum longus (EDL) than soleus. CNTF receptor alpha was increased in unweighted as compared to control soleus muscle, while no significant changes occurred in EDL muscle. Furthermore, CNTF level was not significantly modified in adult sciatic nerve.