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Ultrafast CT scoring system for assessing bronchopulmonary dysplasia: reproducibility and clinical correlation
1Department of Nuclear Medicine, Gunma University School of Medicine, Maebashi, Japan.
Insights
Ultrafast CT (UFCT) scoring is useful for assessing bronchopulmonary dysplasia (BPD) in infants. Hyperaeration, a common finding on UFCT, reliably indicates disease severity.
Area of Science:
- Pediatric Radiology
- Pulmonary Medicine
- Medical Imaging
Background:
- Bronchopulmonary dysplasia (BPD) is a chronic lung disease in infants.
- Accurate monitoring of BPD severity is crucial for effective management.
- Existing imaging methods may have limitations in reproducibility and clinical correlation.
Purpose of the Study:
- To determine the reproducibility of the Ultrafast CT (UFCT) scoring system.
- To assess the utility of UFCT in monitoring the clinical severity of BPD in infants.
Main Methods:
- UFCT scans were analyzed in 22 infants diagnosed with BPD.
- Lung fields were evaluated for specific findings including hyperaeration and opacities.
- Intraobserver and interobserver agreement for UFCT scores were calculated.
- UFCT scores were correlated with clinical severity scores in a subset of patients.
Main Results:
- Hyperaeration was the most frequent finding (81.8%) and demonstrated high reproducibility.
- UFCT scores for hyperaeration showed significant correlation with both intraobserver and interobserver analyses.
- UFCT scores for hyperaeration significantly correlated with clinical severity scores (r = 0.75, p < 0.01).
Conclusions:
- The UFCT scoring system is a valuable tool for assessing BPD in infants.
- Hyperaeration is the most common and reproducible finding on UFCT for BPD.
- The extent of hyperaeration on UFCT correlates significantly with clinical disease severity.
Purpose:
To evaluate the reproducibility of the Ultrafast CT (UFCT) scoring system and assess its usefulness in monitoring clinical severity in infants with bronchopulmonary dysplasia (BPD).
Materials And Methods:
UFCT scoring was done in 22 infants (15 boys and 7 girls aged 1 to 37 months) with BPD. A total of 258 lung fields were evaluated for the presence of hyperaeration, linear opacities, triangular subpleural opacities, and bronchovascular bundle distortion or thickening, and UFCT scores were given. Intraobserver and interobserver agreement and reproducibility of UFCT scores were statistically analyzed. In 12 patients, UFCT scores were linearly correlated with clinical severity scores based on respiratory dysfunction and complexity of care.
Results:
"Hyperaeration," which was the most frequent (18 of 22, 81.8%) finding, showed high concordance (kappa = 0.73, p < 0.001, kappa = 0.59, p < 0.001), and its UFCT scores significantly correlated with intraobserver and interobserver analyses (r = 0.94, p < 0.001, r = 0.82, p < 0.001, respectively). UFCT scores for hyperaeration significantly correlated with clinical scores (r = 0.75, p < 0.01), whereas those for the others did not.
Conclusion:
UFCT is useful for assessing BPD. Hyperaeration was the most common and reproducible finding, and its extent significantly correlated with clinical severity.