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Studying Brain Function in Children Using Magnetoencephalography
Published on: April 8, 2019
Emergency magnetic resonance of the brain
1Department of Radiology, The New York Hospital-Cornell University Medical Center, New York, New York 10021, USA.
Abstract:
We will review the role of magnetic resonance (MR) in assessment of patients with acute neurological abnormalities. The major stumbling block to the use of MR in these patients is the belief that MR is insensitive to hyperacute (<12 h) intracranial hemorrhage and acute subarachnoid hemorrhage (SAH). Hyperacute hemorrhage has characteristic features on MR. Hematomas are iso-to hyperintense on T1-weighted and hyperintense on T2-weighted images. Gradient-echo scans that reveal characteristic peripheral hypointensity are critical to the detection and delineation of hyperacute hematomas. Use of fast fluid-attenuated inversion recovery (FLAIR) sequences has made it possible to detect SAH on MR with a sensitivity that is equal to or greater than computed tomography (CT). SAH produces dramatic hyperintensity in the normally hypointense cerebrospinal fluid on FLAIR. MR has proven useful in the detection of hypertensive encephalopathy and venous thrombosis. These entities can be difficult to diagnose on CT, and in both, early treatment can dramatically improve prognosis. The same is true for acute intracranial infections such as pyogenic abscess, subdural empyema, and herpes simplex encephalitis. MR improves diagnostic accuracy, resulting in more rapid institution of appropriate treatment and improved outcome.
Insights
Magnetic resonance (MR) imaging effectively detects hyperacute intracranial hemorrhage and subarachnoid hemorrhage (SAH), overcoming previous limitations. Advanced MR techniques improve diagnosis of various acute neurological conditions, leading to better patient outcomes.
Area of Science:
- Neurology
- Radiology
- Medical Imaging
Background:
- Magnetic resonance (MR) imaging is crucial for assessing acute neurological abnormalities.
- A key challenge is the perceived insensitivity of MR to hyperacute (<12 hours) intracranial hemorrhage and acute subarachnoid hemorrhage (SAH).
Purpose of the Study:
- To review the role of MR in evaluating patients with acute neurological abnormalities.
- To highlight MR's capabilities in detecting conditions previously challenging for computed tomography (CT).
Main Methods:
- Review of MR imaging characteristics for hyperacute hemorrhage, including T1-weighted, T2-weighted, and gradient-echo sequences.
- Evaluation of fast fluid-attenuated inversion recovery (FLAIR) sequences for detecting SAH.
- Assessment of MR's utility in diagnosing hypertensive encephalopathy, venous thrombosis, and acute intracranial infections.
Main Results:
- Hyperacute hematomas exhibit characteristic iso-to hyperintense T1 and hyperintense T2 signal, with gradient-echo scans showing peripheral hypointensity.
- Fast FLAIR sequences demonstrate high sensitivity for SAH, comparable to or exceeding CT.
- MR aids in diagnosing conditions like hypertensive encephalopathy, venous thrombosis, and infections (abscess, empyema, encephalitis).
Conclusions:
- MR is sensitive to hyperacute intracranial hemorrhage and SAH.
- Advanced MR techniques enhance diagnostic accuracy for a range of acute neurological emergencies.
- Improved diagnostic capabilities with MR facilitate timely treatment and better patient prognoses.
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