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P300 amplitude and antidepressant response to Sudarshan Kriya Yoga (SKY)
P J Naga Venkatesha Murthy1, N Janakiramaiah, B N Gangadhar
1Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.
Background:
There is evidence that Sudarshan Kriya Yoga (SKY) has significant antidepressant effects.
Objective:
The present study examined whether pretreatment P300 ERP amplitude predicts antidepressant response to SKY.
Methods:
Consenting, drug-free depressed patients (n = 30; dysthymics, 15, melancholics, 15) who received SKY as the sole treatment were assessed clinically at pretreatment, 1 month and 3 months. Auditory P300 was recorded before treatment.
Results:
Twenty-two patients responded favourably to SKY. The pretreatment P300 amplitude neither distinguished responders and non-responders nor was associated with differential rates of response.
Discussion:
It is concluded that SKY therapy is uniformly effective regardless of the pretreatment P300 amplitude.