Esophageal carcinoma secondary to a chemical injury in a child
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Updated: Oct 28, 2026

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
Published on: December 23, 2022
S T Schettini1, A Ganc, L Saba
1Department of Pediatric Surgery, Federal University of São Paulo, Escola Paulista de Medicina, and Hospital Infantil Menino Jesus, São Paulo, Brazil.
Abstract:
Twin sisters were clinically and endoscopically followed due to chemical injuries to the esophagus after ingestion of muriatic acid at 10 months of age. One of the girls developed esophageal carcinoma 10 years later and died after esophagectomy because of progression of the disease. Her twin sister has a severe stenosis at the distal esophagus and is waiting for surgical treatment. Malignization of a chemical injury to the esophagus in a child has not yet been described in the literature, emphasizing the role of endoscopic follow-up with periodic biopsies.
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