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Updated: Aug 1, 2026

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models
Published on: August 9, 2012
Augmenting the augmented bladder: treatment of the contractile bowel segment
J C Pope1, M A Keating, A J Casale
1Division of Pediatric Urology, James Whitcomb Riley Hospital for Children, Indianapolis, Indiana, USA.
Re-augmenting the bladder with additional bowel segments can effectively manage high-pressure bladder contractions and improve outcomes after initial enterocystoplasty. This procedure addresses persistent incontinence and upper tract issues in select patients.
Area of Science:
- Urology
- Surgical Innovation
- Patient Outcomes
Background:
- Enterocystoplasty, a common bladder reconstruction technique, can result in residual bowel contractile properties.
- Some patients develop high-pressure bladder contractions post-augmentation, necessitating further intervention.
Purpose of the Study:
- To evaluate the effectiveness of re-augmentation in patients experiencing persistent high-pressure bladder contractions after primary enterocystoplasty.
- To analyze the reasons for repeat augmentation and the outcomes of additional bowel segment placement.
Main Methods:
- Retrospective review of 19 patients requiring repeat bladder augmentation.
- Evaluation of reasons for re-augmentation, upper tract changes, original and secondary bowel segments, and urodynamic findings.
- Assessment of current status and follow-up duration post-re-augmentation.
Main Results:
- Post-initial augmentation complications included incontinence, bladder perforation, upper tract changes, and pain.
- Preoperative urodynamics showed detrusor pressures ranging from 30 to 100 cm H2O.
- Re-augmentation, primarily with ileum, resolved incontinence in 10 of 11 patients and all upper tract changes, with a mean follow-up of 52 months.
Conclusions:
- Re-evaluating bladder dynamics is crucial when enterocystoplasty outcomes are suboptimal.
- Re-augmentation with an additional bowel segment is an effective solution for high-pressure bladder contractions and functionally small bladder capacity.
- This approach significantly decreases contractions and increases functional bladder capacity, leading to favorable clinical outcomes.
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