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Pathophysiological relationships between lower urinary tract symptoms and the prostate do not strengthen over time
A J Lee1, W M Garraway, R J Simpson
1Department of Public Health Sciences, The University of Edinburgh Medical School, Scotland.
Background:
The aim of this survey was to examine the relationships among baseline prostate gland volume and changes in urinary symptomatology 3 years later.
Methods:
A Scottish community-based cohort of 193 men aged 40-79 years who had prostate volume measured by transrectal ultrasound (TRUS) were followed-up at 3 years.
Results:
Only baseline nocturia correlated with prostate volume (r = 0.202, P = 0.0057), although some relationships existed for the antero-posterior dimension of the prostate gland. More statistically significant relationships were evident for adenoma volume rather than prostate volume, but they still had relatively low correlations (range, 0.19-0.31).
Conclusions:
This study demonstrates the lack of relationships between prostate gland variables and lower urinary tract symptoms (LUTS). Those relationships that are statistically significant (at the P < 0.01 level) are weak, and only explain at most 9% of the total variation of prostate or adenoma volume or their dimensions.
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