Competition involving biogenic NO

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A A Nedospasov¹

¹Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, 123182, Russia. nedospas@img.ras.ru

Biochemistry. Biokhimiia

|August 29, 1998

Abstract:

This review considers competitive reactions of NO biosynthesis and its interaction with its targets including enzyme competition for arginine, competition between the substrates in the NO-synthase active sites, competitive sources of arginine, multiple states of NO-synthases resulting from competition of reducible cofactors (FAD, FMN, BH4, heme), competition between aqueous and lipophilic phases for NO resulting in efficient micellar catalysis, and other aspects of competition involving biogenic NO.

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