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Updated: Aug 11, 2026

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Employing Pressurized Hot Water Extraction (PHWE) to Explore Natural Products Chemistry in the Undergraduate Laboratory
Published on: November 7, 2018
Rapid and simple isolation of zingiberene from ginger essential Oil
1Department of Entomology, University of California, Riverside, California 92521, USA.
Journal of Natural Products
|August 29, 1998
Abstract:
A sesquiterpene-enriched fraction of ginger oil was treated with the dienophile 4-phenyl-1,2,4-triazoline-3,5-dione (2), which selectively formed a Diels-Alder adduct with the sesquiterpene hydrocarbon zingiberene (1). The adduct was purified by flash chromatography, then hydrolyzed to return zingiberene in good yield and >99% purity.

