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Aeruginosin 103-A, a thrombin inhibitor from the cyanobacterium Microcystis viridis
S Kodani1, K Ishida, M Murakami
1Laboratory of Marine Biochemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Journal of Natural Products
|August 29, 1998
Abstract:
Aeruginosin 103-A was isolated from the cultured freshwater cyanobacterium Microcystis viridis(NIES-103). Its structure was elucidated to be 1 on the basis of 2D NMR data. This linear peptide inhibited thrombin, with an IC50 of 9.0 microgram/mL.