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Updated: Sep 6, 2026

Visualizing Antigen Specific CD4+ T Cells using MHC Class II Tetramers
15:42

Visualizing Antigen Specific CD4+ T Cells using MHC Class II Tetramers

Published on: March 6, 2009

HIV-2 and T cell recognition

H C Whittle1, K Ariyoshi, S Rowland-Jones

  • 1MRC Laboratories, The Gambia, West Africa. whittle@commit.gm

Current Opinion in Immunology
|September 2, 1998
PubMed

HIV-2 is less pathogenic and less transmissible than HIV-1. Recent research in relation to deletions in the HIV nef gene and to immune cross-reactions between infections by HIV-2, HIV-1 and simian immunodeficiency virus suggests that T cell recognition and the control of viral replication may be more efficient in HIV-2 infection than in HIV-1 infection. These insights may be crucial to the design of effective vaccines.

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