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Predictive value of C-reactive protein after successful coronary-artery stenting in patients with stable angina
A Gaspardone1, F Crea, F Versaci
1Divisione di Cardiochirurgia, Università di Roma Tor Vergata, Rome, Italy.
Insights
Elevated C-reactive protein levels 72 hours post-coronary artery stenting indicate a higher risk of adverse events. Patients with normal C-reactive protein levels showed better outcomes at 12-month follow-up.
Area of Science:
- Cardiology
- Biomarkers
- Inflammation
Background:
- Coronary artery stenting is a common procedure for stable angina pectoris.
- C-reactive protein (CRP) is a marker of inflammation.
- The prognostic value of CRP after stenting requires further investigation.
Purpose of the Study:
- To investigate the association between early plasma C-reactive protein levels and 12-month clinical outcomes in patients undergoing coronary artery stenting for stable angina pectoris.
Main Methods:
- Plasma CRP levels were measured 72 hours after successful coronary artery stenting.
- Seventy-six patients with stable angina pectoris were included.
- Clinical events were assessed at 12-month follow-up.
Main Results:
- Patients with abnormal CRP levels at 72 hours had a higher cumulative event rate at 12 months.
- Patients with normal CRP levels were event-free during the follow-up period.
Conclusions:
- Early postoperative C-reactive protein levels may serve as a predictive biomarker for adverse events after coronary artery stenting.
- Monitoring CRP could help identify high-risk patients needing closer follow-up or intensified therapy.
Abstract:
Plasma levels of C-reactive protein were measured 72 hours after successful coronary artery stenting in 76 patients with stable angina pectoris. At 12-month follow-up, the cumulative event rate was higher in patients with abnormal levels of C-reactive protein than that observed in patients with normal C-reactive protein who were event free.