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Infection with Mycobacterium tuberculosis complicating a pulmonary sequestration
1Department of Thoracic Surgery, University Federico II, Naples, Italy.
The Annals of Thoracic Surgery
|September 2, 1998
Summary
Pulmonary sequestration, a rare lung malformation, can become infected. This case highlights a unique intralobar sequestration infected solely by Mycobacterium tuberculosis, successfully treated with surgery and chemotherapy.
Area of Science:
- Pulmonology
- Infectious Diseases
- Surgical Pathology
Background:
- Pulmonary sequestration is a congenital lung malformation with a propensity for infection, typically by pyogenic bacteria.
- Tuberculosis (TB) is a significant global infectious disease, but its occurrence within pulmonary sequestration is uncommon.
Observation:
- A rare case of intralobar pulmonary sequestration infected exclusively with Mycobacterium tuberculosis is presented.
- The patient had no other identifiable site of tuberculous infection, making this a focal presentation.
Findings:
- Surgical resection of the affected lung lobe was performed.
- Postoperative antituberculous chemotherapy was administered.
- The patient achieved an excellent clinical outcome at 1-year follow-up.
Implications:
- This case expands the spectrum of infectious agents associated with pulmonary sequestration.
- It underscores the importance of considering atypical pathogens like Mycobacterium tuberculosis in the differential diagnosis of infected pulmonary sequestration.
- Successful management involves a combination of surgical intervention and targeted antimicrobial therapy.