Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Maximum cardiac output during incremental exercise by first-pass radionuclide ventriculography

J M Maroni1, D A Oelberg, P Pappagianopoulos

  • 1Pulmonary and Critical Care Unit, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA.

Chest
|September 3, 1998
PubMed
Summary

First-pass radionuclide ventriculography (FPRV) can estimate maximum cardiac output during exercise. This noninvasive method is reliable for patients without left-sided regurgitation, offering a valuable alternative for cardiac output assessment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Restriction Fragment Length Polymorphism Analyses of Iranian Strains of Xanthomonas campestris from Cereals and Grasses.

Plant disease·2019
Same author

Treatment of hepatitis C monoinfection in adults--Dutch national guidelines.

The Netherlands journal of medicine·2013
Same author

Effects of exercise and lifestyle modification on fitness, insulin resistance, skeletal muscle oxidative phosphorylation and intramyocellular lipid content in obese children and adolescents.

Pediatric obesity·2013
Same author

Disseminated Mycobacterium chelonae infection presenting as progressive multifocal osteomyelitis: Report of two cases and a review of the literature.

The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses·2012
Same author

Prediction of response to antiretroviral therapy by human experts and by the EuResist data-driven expert system (the EVE study).

HIV medicine·2010
Same author

Oseltamivir-resistant influenza A(H1N1) viruses detected in Europe during season 2007-8 had epidemiologic and clinical characteristics similar to co-circulating susceptible A(H1N1) viruses.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin·2009

Area of Science:

  • Cardiology
  • Nuclear Medicine
  • Exercise Physiology

Background:

  • Assessing maximum cardiac output during exercise is crucial for evaluating cardiovascular function.
  • Traditional methods like the Fick principle can be invasive.
  • Noninvasive techniques are sought to complement or replace invasive measurements.

Purpose of the Study:

  • To validate a noninvasive method, first-pass radionuclide ventriculography (FPRV), for measuring maximum cardiac output (Qv) during exercise.
  • To compare FPRV-derived Qv with cardiac output measured by the Fick principle (Qf).

Main Methods:

  • Seventy-eight patients underwent incremental cardiopulmonary exercise testing with pulmonary arterial catheterization and FPRV.
  • Cardiac output (Qv) by FPRV was compared to cardiac output by the Fick principle (Qf) at peak exercise.

Related Experiment Videos

  • Statistical analysis, including linear regression, was used to assess the relationship between Qv and Qf.

    • Main Results:

    • Initially, peak Qv showed a linear relationship with Qf (r=0.75, p=0.0001) in patients without left-sided regurgitation.
    • After applying a correction factor derived from earlier data, the corrected peak Qv was tightly related to peak Qf (r=0.90, p<0.001).
    • The corrected FPRV measurement demonstrated good agreement with the Fick principle.

    Conclusions:

    • First-pass radionuclide ventriculography (FPRV) provides a reasonable estimation of maximum cardiac output during incremental exercise.
    • This noninvasive technique is validated for patients in whom left-sided cardiac regurgitant lesions have been excluded.
    • FPRV offers a valuable noninvasive tool for cardiac output assessment in specific patient populations.