Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Heavy metals and fertility

I Gerhard1, B Monga, A Waldbrenner

  • 1Department of Gynecological Endocrinology and Reproduction, University Hospital of Obstetrics and Gynaecology, Heidelberg, Germany.

Journal of Toxicology and Environmental Health. Part A
|September 3, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Health and Clinical Management.

Yearbook of medical informatics·2016
Same author

[Epidemiology of orofacial clefts (1995-2006) in France (Congenital Malformations of Alsace Registry)].

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2012
Same author

Ataxia with oculomotor apraxia type 2: clinical, biological and genotype/phenotype correlation study of a cohort of 90 patients.

Brain : a journal of neurology·2009
Same author

Epidemiological, clinical, paraclinical and molecular study of a cohort of 102 patients affected with autosomal recessive progressive cerebellar ataxia from Alsace, Eastern France: implications for clinical management.

Neurogenetics·2009
Same author

[Problems of randomized studies in complementary medicine demonstrated in a study on mistletoe treatment of patients with breast cancer].

Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine·2004
Same author

Acute psychiatric admission and menstrual cycle phase in women with schizophrenia.

Archives of women's mental health·2003

This study shows that heavy metal body load impacts female infertility. Reducing this load through methods like the DMPS test improved conception chances, offering alternatives to hormonal therapy.

Area of Science:

  • Environmental Health
  • Reproductive Medicine
  • Toxicology

Background:

  • Heavy metals are recognized environmental factors impacting human reproductive health.
  • Infertility affects a significant portion of the population, necessitating research into its diverse causes.
  • Understanding the role of environmental toxicants in fertility is crucial for developing effective interventions.

Purpose of the Study:

  • To investigate the association between urinary heavy metal excretion and various factors contributing to female infertility.
  • To explore the influence of trace element and vitamin administration on heavy metal excretion patterns.
  • To evaluate the effectiveness of reducing heavy metal body load on spontaneous conception rates.

Main Methods:

  • Urinary heavy metal levels were measured in 501 infertile women using the 2,3-dimercaptopropane-1-sulfonic acid (DMPS) test.

Related Experiment Videos

  • Correlations between heavy metal excretion, clinical parameters (age, BMI, nationality), and gynecological conditions were analyzed.
  • The impact of trace element and vitamin supplementation on metal excretion was assessed.

    • Main Results:

    • Significant correlations were identified between specific heavy metals and clinical factors such as age, BMI, and nationality.
    • Associations were also found between heavy metals and gynecological conditions including uterine fibroids, miscarriages, and hormonal disorders.
    • Diagnosis and reduction of elevated heavy metal body burden led to improved spontaneous conception in infertile women.

    Conclusions:

    • The DMPS test is a valuable complementary diagnostic tool for assessing heavy metal body load in infertile women.
    • Reducing heavy metal exposure and body burden can enhance fertility outcomes and improve conception chances.
    • Targeted treatment strategies for heavy metal detoxification offer effective alternatives to conventional hormonal therapies for infertility.