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Familial dysplasminogenemia with central retinal vein and cilioretinal artery occlusion
H Iijima1, T Gohdo, S Tsukahara
1Department of Ophthalmology, Yamanashi Medical University, Tamaho, Japan. hiijima@res.yamanashi-med.ac.jp
Purpose:
To report a 49-year-old woman with unilateral central retinal vein occlusion and ipsilateral cilioretinal artery occlusion who showed familial dysplasminogenemia associated with elevated lipoprotein(a).
Method:
Case report.
Results:
Extensive hemostatic and coagulation studies for causes of thrombosis, as well as family studies, disclosed decreased plasminogen activity without reduction of plasminogen antigen in the patient, her two siblings, and her two children. The patient also showed elevated lipoprotein(a).
Conclusion:
The combination of decreased plasminogen activity and elevated lipoprotein(a) should be considered as a possible cause of retinal vein and artery occlusion.