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Vitreitis and Waldenström's macroglobulinemia
C M Knox1, I G Wong, E L Howes
1Department of Ophthalmology, Frances I. Proctor Foundation, University of California, San Francisco 94122-0944, USA.
American Journal of Ophthalmology
|September 4, 1998
Summary
Waldenström's macroglobulinemia, a lymphoproliferative disorder, can cause vitreitis. This case report details a patient who developed vitreitis 10 years after diagnosis.
Area of Science:
- Ophthalmology
- Hematology
- Oncology
Background:
- Waldenström's macroglobulinemia is a rare lymphoproliferative disorder.
- Vitreitis is inflammation of the vitreous humor in the eye.
Observation:
- A 90-year-old male patient presented with vitreitis.
- The patient had a 10-year history of a lymphoproliferative disorder.
- Pathologic examination revealed small, normal-appearing lymphocytes in the vitreous.
Findings:
- The patient was diagnosed with Waldenström's macroglobulinemia after systemic review.
- Worsening lymphadenopathy was noted.
- Vitreitis developed a decade after the initial lymphoproliferative disorder diagnosis.
Implications:
- This case highlights a potential ocular manifestation of Waldenström's macroglobulinemia.
- Chronic lymphoproliferative diseases may present with vitreitis.
- Ophthalmologists should consider Waldenström's macroglobulinemia in patients with unexplained vitreitis.
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