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Related Experiment Videos

Vitreitis and Waldenström's macroglobulinemia

C M Knox1, I G Wong, E L Howes

  • 1Department of Ophthalmology, Frances I. Proctor Foundation, University of California, San Francisco 94122-0944, USA.

American Journal of Ophthalmology
|September 4, 1998
PubMed
Summary

Waldenström's macroglobulinemia, a lymphoproliferative disorder, can cause vitreitis. This case report details a patient who developed vitreitis 10 years after diagnosis.

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Area of Science:

  • Ophthalmology
  • Hematology
  • Oncology

Background:

  • Waldenström's macroglobulinemia is a rare lymphoproliferative disorder.
  • Vitreitis is inflammation of the vitreous humor in the eye.

Observation:

  • A 90-year-old male patient presented with vitreitis.
  • The patient had a 10-year history of a lymphoproliferative disorder.
  • Pathologic examination revealed small, normal-appearing lymphocytes in the vitreous.

Findings:

  • The patient was diagnosed with Waldenström's macroglobulinemia after systemic review.
  • Worsening lymphadenopathy was noted.
  • Vitreitis developed a decade after the initial lymphoproliferative disorder diagnosis.

Implications:

Related Experiment Videos

  • This case highlights a potential ocular manifestation of Waldenström's macroglobulinemia.
  • Chronic lymphoproliferative diseases may present with vitreitis.
  • Ophthalmologists should consider Waldenström's macroglobulinemia in patients with unexplained vitreitis.