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Effects of immunomodulators on postirradiation recovery in the thymus
1Department of Cellular and Molecular Biology, Faculty of Sciences, Safárik University, Kosice, Slovak Republic.
Physiological Research
|January 1, 1997
Abstract:
The effect of immunomodulatory agents on reparation processes in the thymus was studied in mice injured by a single sublethal or lethal dose of ionizing radiation ranging between 6.5-9.5 Gy. Reparation of thymus weight was not influenced by pretreatment with immunomodulators. Furthermore, the morphological picture did not exhibit appreciable differences between non-protected and protected groups, except for greater proliferation of fibroblasts and macrophages in protected animals.