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Transgenic fish and its application in basic and applied research

T T Chen1, N H Vrolijk, J K Lu

  • 1Biotechnology Center, University of Connecticut, Storrs, USA.

Biotechnology Annual Review
|January 1, 1996
PubMed
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Transgenic fish are created using microinjection, electroporation, or retroviral vectors. These genetically modified fish serve as valuable models for scientific research and biotechnology.

Area of Science:

  • Aquaculture
  • Genetics
  • Biotechnology

Background:

  • Transgenic fish production methods have evolved since 1985.
  • Techniques include microinjection, electroporation, and retroviral vector infection.
  • Various fish species have been successfully modified.

Purpose of the Study:

  • To review the current state of transgenic fish research.
  • To explore potential applications in basic and applied science.

Main Methods:

  • Microinjection of foreign DNA into fish eggs.
  • Electroporation of fish eggs with foreign DNA.
  • Infection of fish eggs with retroviral vectors carrying foreign DNA.

Main Results:

Related Experiment Videos

  • Successful production of transgenic fish across multiple species.
  • Demonstration of foreign DNA integration and expression.
  • Established transgenic fish as experimental models.

    • Conclusions:

    • Transgenic fish technology is well-established.
    • Significant potential for transgenic fish in scientific investigation and biotechnology.
    • Ongoing research continues to refine methods and applications.