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Embryo Microinjection for Transgenesis in Drosophila
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Embryo Microinjection for Transgenesis in Drosophila

Published on: June 7, 2024

Drosophila melanogaster histone H2B retropseudogene is inserted into a region rich in transposable elements

A Akhmanova1, W Hennig

  • 1Department of Physiological Chemistry and Pathobiochemistry, Johannes Gutenberg-Universität, Mainz, Germany.

Genome
|September 8, 1998
PubMed

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The internal coding region of LTR retrotransposons and their mechanism of transposition closely resembles a...
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Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
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Position-effect Variegation

In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
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