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Renal disease in the elderly

A M Davison1

  • 1Department of Renal Medicine, St. James's University Hospital, Leeds, UK.

Nephron
|September 8, 1998
PubMed
Summary
This summary is machine-generated.

Kidney structure and function change with age, impacting drug therapy. Management of kidney failure in older adults should focus on rehabilitation potential, not age alone.

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Area of Science:

  • Nephrology
  • Geriatric Medicine
  • Pharmacology

Background:

  • Aging alters kidney structure and function.
  • These age-related renal changes affect patient management, especially drug therapy.
  • Clinical presentation of kidney diseases in the elderly may differ from younger populations.

Purpose of the Study:

  • To review the impact of age-related kidney changes on patient management.
  • To discuss the prevalence and causes of glomerulonephritis and tubulointerstitial nephritis in the elderly.
  • To outline optimal management strategies for end-stage renal failure in older adults.

Main Methods:

  • Literature review of age-related kidney changes.
  • Analysis of clinical presentation and management of glomerulonephritis and tubulointerstitial nephritis in elderly patients.

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  • Discussion of treatment approaches for end-stage renal failure in geriatrics.

    • Main Results:

    • Glomerulonephritis prevalence is likely similar in elderly and younger patients, with differences attributed to clinical practice.
    • Tubulointerstitial nephritis may be more prevalent in the elderly, often linked to drug therapy.
    • Age-related kidney changes necessitate careful consideration in drug selection and dosing.

    Conclusions:

    • Management of kidney diseases in the elderly requires understanding age-specific renal alterations.
    • Drug-induced tubulointerstitial nephritis is a significant concern in older patients.
    • End-stage renal failure management in the elderly should prioritize rehabilitation capacity over chronological age.