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Haemophilus paraphrophilus; a rare cause of intracranial abscess

A J Hart1, P Thompson, A T Casey

  • 1Department of Neurosurgery, The National Hospital for Neurology and Neurosurgery, London, UK.

The Journal of Infection
|November 20, 1998
PubMed

Insights

A rare intracranial abscess caused by Haemophilus paraphrophilus was successfully treated with cefotaxime in a 42-year-old man. This case highlights a potential mechanism for this unusual brain infection.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Microbiology

Background:

  • Intracranial abscesses are serious infections of the brain.
  • Haemophilus species are typically associated with oropharyngeal infections.
  • Neurological symptoms can indicate serious intracranial pathology.

Observation:

  • A 42-year-old man presented with neurological deficits.
  • Imaging revealed an intracranial abscess.
  • Stereotactic aspiration yielded a pure culture of Haemophilus paraphrophilus.

Findings:

  • Haemophilus paraphrophilus was identified as the causative agent of the intracranial abscess.
  • The patient demonstrated a positive clinical response to cefotaxime treatment.
  • A potential mechanism for the infection was proposed.

Implications:

  • This case expands the known spectrum of Haemophilus paraphrophilus infections.
  • It underscores the importance of considering diverse pathogens in intracranial abscesses.
  • Understanding the infection mechanism may guide future treatment strategies.

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