Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

CO2-induced panic attacks: a twin study

L Bellodi1, G Perna, D Caldirola

  • 1Department of Neuropsychiatric Sciences, Istituto Scientifico H.S. Raffaele, Milan, Italy.

The American Journal of Psychiatry
|September 12, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Attitudes towards adjunctive surgical therapy for pulmonary TB in Europe: an ESGMYC, ESTS, and TBnet collaborative survey.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2026
Same author

Black Hole Spectroscopy and Tests of General Relativity with GW250114.

Physical review letters·2026
Same author

GW250114: Testing Hawking's Area Law and the Kerr Nature of Black Holes.

Physical review letters·2025
Same author

Prevalence of sacroiliitis on magnetic resonance enterography in Crohn's disease and its association with intestinal findings: a monocentric observational cross-sectional study.

Clinical and experimental medicine·2025
Same author

Deciphering the Instability of the Black Hole Ringdown Quasinormal Spectrum.

Physical review letters·2024
Same author

Crossing the border between epileptic and vascular pathology: a report of CACNA1A-related treatment-resistant hemiplegic migraine.

Journal of neurology·2023
Same journal

2026 Annual Meeting: President-Elect Address.

The American journal of psychiatry·2026
Same journal

2026 Annual Meeting: CEO and Medical Director's Address.

The American journal of psychiatry·2026
Same journal

Reports to the Membership.

The American journal of psychiatry·2026
Same journal

Convergent Metabolic Dysregulations But Divergent Contributing Pathways Across Severe Mental Disorders: The Power of Combining Genetics and Metabolomics.

The American journal of psychiatry·2026
Same journal

2026 Annual Meeting: Presidential Address.

The American journal of psychiatry·2026
Same journal

Represcribing Previously Used Antipsychotics: Response to So.

The American journal of psychiatry·2026
See all related articles

Genetic factors play a significant role in 35% carbon dioxide (CO2)-induced panic attacks. Higher concordance rates in identical twins suggest a heritable component to panic disorder susceptibility.

Area of Science:

  • Psychiatry
  • Genetics
  • Behavioral Science

Background:

  • Panic attacks can be triggered by various stimuli.
  • The role of genetic predisposition in panic disorder is not fully understood.

Purpose of the Study:

  • To investigate the influence of genetic factors on panic attacks induced by 35% carbon dioxide (CO2).

Main Methods:

  • Ninety twins from the general population underwent challenge testing with 35% CO2-65% O2 inhalations.
  • Probandwise concordance rates were calculated and compared between monozygotic (identical) and dizygotic (fraternal) twins.

Main Results:

  • A significantly higher concordance rate for 35% CO2-induced panic attacks was observed in monozygotic twins (55.6%) compared to dizygotic twins (12.5%).

Related Experiment Videos

Conclusions:

  • The findings indicate a substantial contribution of genetic factors to the susceptibility of experiencing panic attacks when exposed to 35% CO2.
  • These results support the heritability of panic disorder and inform future research into specific genetic markers.