Iodine-123 BMIPP and Ga-67 scintigraphy in liposarcoma

A patient with recurrent retroperitoneal liposarcoma had multiple suspected metastases. I-123 BMIPP imaging showed areas of increased uptake due to accumulation in the myxoid components of the liposarcoma. Ga-67 showed accumulation in the undifferentiated components. The well-differentiated components showed little accumulation of either I-123 BMIPP or Ga-67. Differences in the accumulation of these radionuclides may reflect differences in cell densities, fatty acid metabolism, and the degree of malignancy. I-123 BMIPP and Ga-67 scintigraphy may be useful in determining the prognosis of liposarcoma.