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Related Experiment Videos

Sex differences in ventricular function in patients with right bundle branch block

M R Allen1, R J Gibbons, A R Zinsmeister

  • 1Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minn 55905, USA.

American Heart Journal
|September 15, 1998
PubMed
Summary
This summary is machine-generated.

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Right bundle branch block affects left ventricular ejection fraction differently in men and women. Male patients with this condition show a reduced ejection fraction, unlike female patients, impacting cardiac function assessments.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Cardiac Imaging

Background:

  • Right bundle branch block (RBBB) presence leads to variable left ventricular (LV) function.
  • Assessing LV function in RBBB patients with suspected coronary artery disease (CAD) is crucial.

Purpose of the Study:

  • To evaluate the impact of RBBB on estimating resting LV function.
  • To compare LV function in patients with RBBB versus normal electrocardiograms (ECGs).

Main Methods:

  • Seventy-four RBBB patients with suspected CAD and no Q waves were compared to 649 normal ECG controls.
  • Resting ejection fraction (REJ) was measured using radionuclide ventriculography.

Main Results:

  • RBBB patients were older and had a lower mean REJ than controls (60%±11% vs. 63%±9%, P<0.005).

Related Experiment Videos

  • A significant interaction between RBBB and sex on REJ was observed (P<0.001).
  • Men with RBBB had lower REJ (57%±10%) than normal men (62%±8%), with more abnormal REJ in the RBBB group (17% vs. 7%). Women with RBBB had higher REJ (68%±9%) than normal women (65%±9%).

    • Conclusions:

    • Male patients with RBBB and suspected CAD exhibit reduced resting LV ejection fraction compared to males without RBBB.
    • This disparity in ejection fraction due to RBBB is not observed in female patients.