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Adaptation of Madin-Darby canine kidney cells to hypertonic medium: an electron microprobe analysis
1Department of Physiology, University of Munich, Germany.
Abstract:
Madin-Darby canine kidney (MDCK) cells of confluent epithelial sheets grown on permeable supports respond to hyperosmotic stress by short- and long-term regulatory volume increase (RVI). Although short-term RVI includes the uptake of inorganic electrolytes, long-term RVI does not and seems therefore to result from accumulation of organic osmolytes.
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