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Related Experiment Videos

Improved taste acceptability for an oral hyperalimentation dosage form

C R Behl, B P Agarwala, R A Giudici

    American Journal of Hospital Pharmacy
    |October 1, 1976
    PubMed
    Summary

    Flavoring agents were tested to improve the taste of Vivonex-HN, an oral nutritional supplement. A combination of rum, strawberry, and raspberry flavors with sodium saccharin sweetener was found to be the most acceptable option.

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    Area of Science:

    • Nutritional Science
    • Food Science

    Background:

    • Vivonex-HN is a potent oral hyperalimentation diet.
    • Improving the taste acceptability of nutritional supplements is crucial for patient adherence.

    Purpose of the Study:

    • To evaluate various flavoring agents for their ability to enhance the taste of Vivonex-HN.
    • To identify optimal flavor combinations and sweetener concentrations for improved palatability.

    Main Methods:

    • Incorporation of imitation flavors into Vivonex-HN powder at different concentrations.
    • Evaluation of flavored mixtures with and without sodium saccharin sweetener.
    • Sensory analysis by a taste panel to rate acceptability.

    Main Results:

    • Unsweetened: Orange juice, mint, and cherry mint were most acceptable.

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  • Sweetened (0.025% sodium saccharin): Rum, strawberry, and raspberry were most acceptable.
  • Optimal formulation: A combination of rum, strawberry, and raspberry with 0.025% sodium saccharin.

    • Conclusions:

    • Flavor modification can significantly improve the taste acceptability of Vivonex-HN.
    • Specific flavor profiles and sweetener combinations are more effective than others.
    • The identified optimal formulation offers a promising strategy for enhancing patient compliance with oral nutritional therapy.