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Decrease in prevalence of Buerger's disease in Japan

M Matsushita1, N Nishikimi, T Sakurai

  • 1First Department of Surgery, Nagoya University School of Medicine, Japan.

Surgery
|September 16, 1998
PubMed
Summary
This summary is machine-generated.

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Buerger's disease (thromboangiitis obliterans) prevalence is decreasing in Japan, with no changes in its clinical characteristics. This trend mirrors observations in Western countries, suggesting a potential global decline in this rare peripheral arterial disease.

Area of Science:

  • Vascular Surgery
  • Epidemiology
  • Clinical Medicine

Background:

  • Buerger's disease, a rare peripheral arterial occlusive disease, exhibits varying prevalence globally, being less common in Western countries and more prevalent in Asia.
  • The classification of Buerger's disease as a distinct entity remains a subject of ongoing debate within the medical community.

Purpose of the Study:

  • To investigate the changing prevalence and clinical characteristics of Buerger's disease.
  • To analyze trends at a major Japanese medical institution over a defined period.

Main Methods:

  • Retrospective analysis of patients diagnosed with Buerger's disease at Nagoya University Hospital (1985-1996).
  • Diagnosis adherence to Shionoya's clinical criteria.
  • Evaluation of admission data for new cases and disease exacerbations.

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Main Results:

  • A significant decrease in new Buerger's disease admissions was observed from 1985-1989 (46 patients) to 1990-1996 (12 patients) (p=0.0003).
  • Admissions for disease exacerbation also declined significantly during the study period (p=0.0137).
  • Patient demographics showed a majority of males (96%) with a mean age of onset at 36 years; gangrene/ulcer was the most common presenting complaint (64%).

Conclusions:

  • The prevalence of Buerger's disease is declining at the studied Japanese institution.
  • Clinical features of Buerger's disease have remained consistent.
  • This observed decrease in prevalence aligns with trends previously reported in Western nations.