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Related Experiment Videos

Awareness and responsiveness during partial seizures

Y Inoue1, T Mihara

  • 1National Epilepsy Center, Shizuoka Higashi Hospital, Urushiyama, Japan.

Epilepsia
|September 16, 1998
PubMed
Summary
This summary is machine-generated.

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Most patients with partial seizures (PS) are aware of their condition. Impaired awareness during seizures is linked to specific frontal lobe epilepsy (FLE) and temporal lobe epilepsy (TLE) origins.

Area of Science:

  • Epilepsy and Consciousness Research
  • Clinical Neurology
  • Intracranial EEG Studies

Background:

  • Partial seizures (PS) are classified by altered awareness and/or responsiveness.
  • Understanding consciousness impairment during PS is crucial for diagnosis and treatment.
  • Previous research has not fully elucidated the relationship between seizure origin and awareness.

Purpose of the Study:

  • To examine consciousness impairment during partial seizures (PS) originating from various brain sites.
  • To correlate seizure origin, laterality, and EEG findings with awareness and responsiveness.
  • To evaluate the clinical utility of the term 'complex partial seizures' (CPS).

Main Methods:

  • Analysis of 142 patients undergoing intracranial EEG and resective surgery.

Related Experiment Videos

  • Assessment of patient awareness of seizures and review of videotaped seizures with EEG.
  • Evaluation of responsiveness and recall during ictal events and stimuli.

    • Main Results:

    • 114 out of 142 patients reported awareness of their seizures.
    • Impaired awareness was associated with frontal lobe epilepsy (FLE) on the language-nondominant side and temporal lobe epilepsy (TLE) in the lateral language-dominant cortex.
    • Bilateral seizure discharge spread correlated with reduced responsiveness; recall of stimuli was limited to some FLE patients.

    Conclusions:

    • Altered awareness and responsiveness occur in the majority of habitual partial seizures.
    • Specific seizure origins and bilateralization predict impaired consciousness during PS.
    • The term 'complex' remains clinically relevant for describing partial seizures with altered awareness.